Pregnancy Outcomes in Thalassemia: Impact Factors and Optimized Management Strategies

Understanding the Impact Factors on Maternal and Neonatal Outcomes in Women with Thalassemia during Pregnancy

Objective:

We med to explore the factors influencing maternal and neonatal outcomes among women pregnant with thalassemia, commonly known as thalassemia. This investigation was conducted through a retrospective study at the Women's and Children Health Center of Bishan City from June 2016 to February 2019.

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A cohort of 64 singleton pregnancies affected by thalassemia were identified and compared agnst a control group consisting of 56 healthy singleton pregnancies matched for age, gestational age, and other pertinent parameters. The data on clinical indicators such as hemoglobin levels, anemia severity, and other maternal health metrics were recorded.

Data Analysis:

The collected data was thoroughly analyzed to determine the incidence of adverse pregnancy outcomes, which included premature delivery, low birth weight infants, and fetal loss among women with thalassemia compared to those in the control group. The research findings were then segmented into two categories: non-favorable maternal-neonatal outcomes and favorable outcomes.

Key Findings:

The analysis revealed that women pregnant with thalassemia faced higher risks of adverse pregnancy outcomes, including low birth weight infants 12 vs. 3 and premature deliveries 28 vs. 7. Hemoglobin levels below the recommed threshold were significantly correlated with an increased risk of these negative outcomes.

Furthermore, a comprehensive review of literature indicated that adequate prenatal care, regular monitoring for thalassemia-specific complications, and timely intervention in cases of acute iron overload could mitigate risks associated with pregnancy in women affected by thalassemia. These findings emphasize the critical role of comprehensive obstetric management to ensure positive outcomes.

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The study underscores the importance of meticulous prenatal screening for thalassemia, continuous monitoring during pregnancy, and effective treatment strategies med at managing complications related to maternal anemia. A proactive approach towards healthcare services can significantly influence the favorable outcomes of pregnancies in women with thalassemia. It is thus recommed that women diagnosed with thalassemia receive specialized obstetric care tlored to their specific health needs.

This research contributes valuable insights into understanding the multifactorial impact on maternal and neonatal outcomes, which could inform healthcare professionals and policy makers for better management of pregnancies affected by thalassemia. The ultimate goal is to optimize reproductive health among women with this condition and enhance the overall quality of life for the newborns.

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